Results 91 to 100 of about 172,262 (269)

Kuwait Water Harvesting System: Final Report [PDF]

open access: yes, 1990
Kuwait Water Harvesting System Final Report, Submitted To: Kuwait Institute For Scientific ResearchIntroduction: The potential of water harvesting is sometimes overlooked in areas of low rainfall that is less than 200 mm. However it is precisely in these
Cluff, C. Brent
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Cost Effectiveness of Rainwater Harvesting for Groundwater Recharge in Micro-Watersheds of Kolar District of India: The Case Study of Thotli Micro-Watershed [PDF]

open access: yes
This study has estimated the supply augmentation of groundwater recharge due to creation of water harvesting structures and has assessed the cost-effectiveness of rainwater harvesting for groundwater recharge on watershed basis in one of the sub ...
Nagaraj, N.   +4 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Rainwater harvesting, alternative to the water supply in Indian urban areas : The case of Ahmedabad in Gujarat [PDF]

open access: yes
Water scarcity is a characteristic of north-western states of India, such as Gujarat. Over time, the continuous increase of the population as well as the financial, administrative and technical deficiencies of the new supply system have lead to the ...
Akil Amiraly, Nathalie Prime, J.P. Singh
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

CREATING AGRIBUSINESS OPPORTUNITIES FOR SMALL SCALE FARMERS IN THABA NCHU BY INTRODUCING WATER HARVESTING TECHNIQUES: A PROFITABILITY AND RISK ANALYSIS [PDF]

open access: yes
Thaba Nchu is a semi-arid area with low and erratic annual rainfall not exceeding 600mm. Various dryland crops are produced with relatively low yields and high risk of failure.
Baiphethi, Mompati N.   +2 more
core   +1 more source

Rainwater harvesting potential in Sydney : are we harvesting enough? [PDF]

open access: yes, 2016
Rainwater harvesting has become popular in Australian urban areas due to water restrictions, greater environmental awareness, government regulations and incentives for installation of rainwater harvesting systems. It can provide non-potable water to meet
Rahman, Ataur (R9573)   +1 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Household water security through stored rainwater and consumer acceptability: a case study of the Anuradhapura District [PDF]

open access: yes
Rainwater harvesting has increased in popularity in Sri Lanka over the past two decades due to the number of water supply projects funded by the government and non-governmental organizations (NGOs).
De Silva, R. P.   +2 more
core  

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