Results 71 to 80 of about 5,361,862 (301)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Evaluation and Comparison of Precipitation Datasets by Reanalysis and Satellite Models in Different Parts of Iran [PDF]
Water Harvesting ResearchRainfall is a crucial component of the hydrological cycle and plays a key role in water resource planning. Recent research has investigated the use of gridded data as a supplement to and replacement for traditional rain gauge measurements, particularly ...
Ali Gorjizade
doaj +1 more source
Rainwater Harvesting Potential for Domestic Water Supply in Edo State [PDF]
In the face of increasing scarcity of water resources, there is a need for communities to undertake audits of their current rainwater harvesting potential as a practical and promising alternative solution for water shortage.
S. I. Oni, Emmanuel Ege
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Kuwait Water Harvesting System: Final Report
, 1990 Kuwait Water Harvesting System Final Report, Submitted To: Kuwait Institute For Scientific ResearchIntroduction: The potential of water harvesting is sometimes overlooked in areas of low rainfall that is less than 200 mm. However it is precisely in these
Cluff, C. Brent
core +4 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
SN Applied Sciences, 2019 Water scarcity is at the center of the world’s greatest challenges, including famine, disease, and sustainable development. In many countries, there are active researches aimed at improving the supply of fresh water through actions such as seawater desalination and water recycling. Researchers are also working, on a smaller scale, to harvest water from
openaire +2 more sources
Rainwater harvesting, alternative to the water supply in Indian urban areas : The case of Ahmedabad in Gujarat [PDF]
Water scarcity is a characteristic of north-western states of India, such as Gujarat. Over time, the continuous increase of the population as well as the financial, administrative and technical deficiencies of the new supply system have lead to the ...
Akil Amiraly, Nathalie Prime, J.P. Singh
core
Water harvesting: guidelines to good practice [PDF]
, 2013 These guidelines provide an overview of proven good practice in water harvesting from all over the world. They form a practical reference guide while providing support and specific technical expertise for the integration of water harvesting technologies ...
Mekdaschi Studer, Rima +1 more
core +1 more source