Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Prototype Development of a Two-Stage Hydrogel–CaCl₂ Absorption–Desorption Device for Atmospheric Water Harvesting [PDF]
Freshwater scarcity has become a pressing global challenge, driving the need for innovative and sustainable water production technologies. Atmospheric water harvesting offers a promising solution by exploiting the vast reservoir of water vapor in the air,
Sajjad Ghasemi, Mohammad Fazaelipoor
doaj +1 more source
Evaluation and Simulation of Groundwater Flow in Aquifers Enclosed With Desert Saline Areas (Case Study: Isfahan Province-Ardestan Aquifer) [PDF]
Quantitative changes in groundwater and crises resulting from uncontrolled water extraction have turned water resources management into one of the supply-demand dilemmas in arid regions.
Saman Javadi +2 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Converting rain into drinking water: Quality issues and technological advances [PDF]
With growing pressures on water supplies worldwide, rainwater harvesting is increasingly seen as a viable option to provide drinking water to an ever expanding population, particularly in developing countries.
Hudson-Edwards, KA +7 more
core +1 more source
Climate Variability and Industrial Groundwater Abstraction in a Water-Stressed Petroleum Basin: Water Demand Dynamics in Lokichar Oil Production Wells, Kenya [PDF]
The Lokichar Basin in Turkana, northern Kenya, is a semi-arid environment marked by pronounced rainfall variability and intense competition for water resources among domestic, livestock, and oil-driven industrial demands.
Mary Makokha, Martin Kalibbala
doaj +1 more source
Investigation on Climate Change in Meteorological Stations of Guilan Province and its Impacts on Water Balance [PDF]
Climate has always been changing during the lifetime of the earth, and has appeared in the form of the ice age, hurricanes, severe and sudden temperature changes, precipitation and other climatic elements, and has dramatically influenced the environment,
jalal Behzadi
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Investigating the Impacts of Climate and Land Use Change on the Hydrologic Characteristics in the Sub-Basins of the Dez River, Middle East [PDF]
Human activities and the climate change affects the river flow therefore monitoring flow rate of river for an extended period can reveal the detail of involved mechanisms in these changes.
Zohreh Khorsandi Kouhanestani
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

