We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Domesticating water supplies through rainwater harvesting in Mumbai [PDF]
Mumbai is a city where 60 per cent of the population are living in poverty in informal settlements, with low – and decreasing – water access, and low resilience to water shortage.
Cat Button, Button, Cat
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Atmospheric Water Harvesting: the role of materials in condensing technologies [PDF]
openLa raccolta dell'acqua dall’atmosfera (Atmospheric Water Harvesting) sta emergendo come una promettente alternativa per far fronte alla crescente domanda globale d’acqua, in particolare nelle regioni aride.
CORAZZA, LISA
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Up-scaling of rainwater harvesting for crop production in the communal lands of the Modder River basin in South Africa: comparing upstream and downstream scenarios [PDF]
Published ArticleThe study area is the Upper and Middle Modder River basin situated in a semi-arid area of central South Africa. This is an important catchment because of the relatively large nearby towns of Bloemfontein, Botshabelo and Thaba Nchu.
M Hensley +9 more
core +1 more source
A Risk-Based Reservoir Health Indicator for Long-Term Water Quality Assessment: Application to Dissolved Oxygen in Minab Dam [PDF]
Dissolved oxygen (DO) fluctuations directly affect biological processes and water quality in a reservoir. It can occur gradually or rapidly as a result of a large input load of pollution.
Hamid Abdolabadi
doaj +1 more source
Prioritizing Suitable Lands for Flood Spreading for Artificial Discharge using Integrated Model AHP / Fuzzy (Case Study: Shourdasht Basin) [PDF]
During recent years, increasing exploitation of groundwater aquifers has caused a substantial and sharp drop in groundwater table in the plains of Iran.
Mohammad Reza Jebraeili, Parvin Zarei
doaj +1 more source

