Results 41 to 50 of about 5,053,766 (248)
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Performance optimization of an air source heat pump water heater using mathematical modelling
Journal of Energy in Southern Africa, 2017 In South Africa, there is an ongoing constraint on the electricity supply at the national grid to meet the demand. Eskom is implementing various measures such as the Integrated Demand Management and the promotion and encouragement of the use of energy ...
Stephen Tangwe +4 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Comparison of aluminium and stainless steel built-in-storage solar water heater
, 2007 This article provides the results and findings of an experimental work undertaken in Pakistan that aimed to compare the performance of stainless steel and aluminium make built-in-storage solar waters.
Muneer, T., Asif, M., Currie, J.
core +1 more source
Langage articulé par le chauffe-eau dans La Carte et le territoire : entre l’étrangeté et l’intimité
Relief: Revue Électronique de Littérature Francaise, 2018 La dizaine d’apparitions du chauffe-eau dans La Carte et le territoire ne semble pas anodine. En contextualisant cette machine sous la plume de Houellebecq, le présent article se propose d’interpréter les liens entre le chauffe-eau et le style de l ...
Hua Hu
doaj +5 more sources
Measurement + ControlThe high value of aero-engines makes it necessary to extend their life in terms of econ-omy of use. Health management is an important basis for this work.
Mai Xin, Zhifeng Ye, Xing Liu, Xiong Pan
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Advances in Mechanical Engineering, 2016 An instantaneous-heating air source heat pump water heater with a temperature stratified water tank was put forward. The instantaneous-heating air source heat pump water heater was designed to produce hot water instantly by three modes, namely condenser ...
Mingjing Lei +3 more
doaj +1 more source