Results 91 to 100 of about 28,018 (296)

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Seed Germination in Ginkgo biloba L. I. Influences of Cold Treatment, Gibberellic Acid and Red Light [PDF]

, 1974
The influences of cold treatment, gibberellic acid and red light treatment on rate of germination of seeds of Ginkgo biloba L. were followed for a 12-wk period. Dispersal units were collected, and the outer fleshy layer was removed soon after harvest. Of
Johnson, Michael I., Wickliff, James L.
core   +2 more sources

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Water Uptake by Seeds in Yellow-seeded Soybean (Glycine max (L.) Merrill) Cultivars with Contrasting Imbibition Behaviors

Plant Production Science, 2008
The rate of water uptake by seeds is assumed to be an important factor affecting the susceptibility of seeds to flooding injury, but the traits which could contribute to restricting rapid imbibition by seeds remain undetermined in yellow-seeded soybeans.
Norikazu Nakayama, Setsuko Komatsu
doaj   +1 more source

Two-dimensional hydrodynamic lattice-gas simulations of binary immiscible and ternary amphiphilic fluid flow through porous media

, 2000
The behaviour of two dimensional binary and ternary amphiphilic fluids under flow conditions is investigated using a hydrodynamic lattice gas model. After the validation of the model in simple cases (Poiseuille flow, Darcy's law for single component ...
B. M. Boghosian, B. M. Boghosian, C. Zarcone, D. H. Rothman, D. H. Rothman, D. H. Rothman, F. Kalaydjian, J. F. Olson, J.-B. Maillet, J.-B. Maillet, L. P. Kadanoff, P. A. Goode, P. V. Coveney, P. V. Coveney, Peter V. Coveney, S. Wolfram, U. Frisch   +16 more
core   +1 more source

Capillary Imbibition Laws of Fresh–Brackish Waters in Sandstone

Water
Understanding the capillary imbibition laws of brackish water in rocks is necessary to reveal the mechanism of fluid, salt, and ion transport. In this study, we investigated the capillary imbibition laws of a Na2SO4 solution of different concentrations in sandstone by measuring the parameters of water absorption mass, water migration front height ...
Hailiang Jia, Xiaoyu Yang, Yao Wei, Qiang Sun, Liyun Tang   +4 more
openaire   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Numerical Study on the Effects of Imbibition on Gas Production and Shut-In Time Optimization in Woodford Shale Formation

Energies, 2020
In shale gas formations, imbibition is significant since the tight pore structure causes a strong capillary suction pressure. After hydraulic fracturing, imbibition during the period of shut-in affects the water recovery of flowback.
Zhou Zhou, Shiming Wei, Rong Lu, Xiaopeng Li   +3 more
doaj   +1 more source

Dormición física de las semillas de leguminosas nativas de Argentina [PDF]

, 2016
Leguminosae es una familia con un alto valor de uso como alimento, forraje, medicina y para fines ornamentales y de restauración ecológica. Uno de los principales problemas para el uso y manejo de muchas de estas especies es la presencia de semillas con ...
Bach, Hernán Gerónimo, Ceccato, Diana, Chilo, Gladys, Fortunato, Renée Hersilia, Galindez, Guadalupe, Malagrina, Gisela, Ortega Baes, Francisco Pablo, Pidal, Barbara   +7 more
core  

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source