Results 51 to 60 of about 362,459 (244)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Offspring born to ewes fed high salt during pregnancy have altered responses to oral salt loads

open access: yesAnimal, 2010
Prenatal growth is sensitive to the direct and indirect effects of maternal dietary intake; manipulation can lead to behavioural and physiological changes of the offspring later in life.
S.N. Digby   +4 more
doaj   +1 more source

Optimization of the Operation of Groundwater Intakes Using Two-Column Wells

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2022
The average number of wells at a typical water intake is 30–40; while the power of the submersible pump is usually 32–40 kW; which means that only at one well water intake the power consumption of electric pumping equipment during the hours of greatest ...
V. V. Ivashechkin, J. A. Medvedeva
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The effect of varying duration of water restriction on drinking behaviour, welfare and production of lactating sows

open access: yesAnimal, 2016
Access to drinking water is essential for animal welfare, but it is unclear if temporary water restriction during the night represents a welfare problem.
M.B. Jensen   +4 more
doaj   +1 more source

Water Intake, Water Balance, and the Elusive Daily Water Requirement [PDF]

open access: yesNutrients, 2018
Water is essential for metabolism, substrate transport across membranes, cellular homeostasis, temperature regulation, and circulatory function. Although nutritional and physiological research teams and professional organizations have described the daily total water intakes (TWI, L/24h) and Adequate Intakes (AI) of children, women, and men, there is no
Lawrence E. Armstrong, Evan C. Johnson
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Multiple Beneficial Effects of Ghrelin Agonist, HM01 on Homeostasis Alterations in 6-Hydroxydopamine Model of Parkinson’s Disease in Male Rats

open access: yesFrontiers in Integrative Neuroscience, 2019
Background and objective: Developing therapy for non-motor symptoms of Parkinson’s disease (PD) is important for improving patients’ quality of life.
Artem Minalyan   +6 more
doaj   +1 more source

WATER INTAKE PATTERNS

open access: yesInternational Journal For Multidisciplinary Research
The current research titled, “Water Intake Patterns” is a comparative study aged 16-25 between girls and boys pertaining to overall effects due to inadequate quantity of water ...
Bhagyashree Kulkarni -, Anmol Deshmukh -
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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