Results 31 to 40 of about 3,772,219 (301)

Can water, energy, and food policies in support of solar irrigation enable gender transformative changes? Evidence from policy analysis in Bangladesh and Nepal

open access: yesFrontiers in Sustainable Food Systems
Solar irrigation pumps (SIPs) are emerging as a popular technology to address water, energy, and climate change challenges in South Asia while enhancing livelihoods and food security.
Manohara Khadka   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Operational sentinel-2 system for monthly near‑real‑time irrigated area mapping in the Limpopo river basin

open access: yesDiscover Water
Monitoring irrigated agriculture is critical in the water-scarce Limpopo River Basin (LRB). However, existing approaches are often coarse, retrospective, or season-aggregated, which limits their ability to capture smallholder irrigation and the month-to ...
Zolo Kiala   +5 more
doaj   +1 more source

Reducing soil degradation to increase resilience to climate change and strengthen livelihoods in Ethiopia. [PDF]

open access: yes, 2019
Soil degradation is a major problem in Ethiopia. Depletion of soil organic matter is a cause of low agricultural productivity, as soils become less fertile and less resilient to extreme weather events, which are expected to increase with climate change ...
International Water Management Institute
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Factors affecting willingness to adopt climate insurance among smallholder farmers in Sri Lanka

open access: yesClimate Risk Management, 2023
Drought is an almost annual phenomenon affecting many parts of Sri Lanka, causing huge damage to agriculture and losses to the broader economy in general and farmers in particular. Climate change threatens to exacerbate these risks.
Mohamed Aheeyar   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Security in flexibility: accessing land and water for irrigation in Kenya’s changing rural environment

open access: yesCahiers Agricultures, 2022
In the semi-arid lands of southern Kenya, a dynamic process of farmer-led irrigation has developed over the past two decades. It is characterised by short-term agreements to access land and water. Resident and migrant farmers, capital providers and local
Duker Annelieke E.C.   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Water marketing effects on crop-water management

open access: yesCalifornia Agriculture, 1989
This study considers a water marketing system in which farmers can buy a given amount of water, at a fixed price, and sell the amount not used. The system could induce farmers to upgrade their irrigation systems and reduce water application and drainage ...
J Letey, A Dinar
doaj  

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