Results 41 to 50 of about 1,501,393 (262)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
SUBTROPICAL WATER MASSES IN HALMAHERA WATERS
Jurnal Ilmu dan Teknologi Kelautan Tropis, 2010 <p>Research of water masses by using conductivity temperature depth (CTD), are conducted in the eastern path of the Indonesia Throughflow (ITF) in the Halmahera, Seram and Banda seas during March-April 2007 under the Expedition of Widya Nusantara (EWIN). The objective of this research is to see maximum salinity spread of South Pacific Subtropical
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Advances in Civil Engineering, 2023 Soil-rock mixtures (S-RMs), as special engineering geological materials, are widely distributed in mountainous regions and are important hosts of slope disasters.
Wenwei Gao +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Impacts of Winter and Spring Water Masses on Demersal Fish Community Structure Around Hainan Island
AnimalsTo elucidate water mass impacts on fish diversity in Hainan Island, bottom trawl surveys were conducted at 50 stations around the Island in December 2023 (winter) and April 2024 (spring).
Boran Qin +6 more
doaj +1 more source
Agriculture, 2023 Soil fertility decline is a significant drawback to food and nutritional security in sub-Saharan Africa. However, information and knowledge barriers seriously impede the adoption, effective use, and scaling up of soil fertility management innovations ...
Pamellah A. Asule +5 more
doaj +1 more source