Results 121 to 130 of about 1,031,461 (308)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Ingestive behaviour and physiology of the medicinal leech [PDF]
, 1988 Ingestion lasts 25 min in Hirudo medicinalis and is characterized by pharyngeal peristalsis which fills the crop. This peristalsis has an initial rate of 2.4 Hz which decays smoothly to 1.2 Hz at termination of ingestion. During ingestion, the leech body
Dickinson, M. H. +3 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
The Effect of Glucose on Fetal Movement
مجله دانشکده پزشکی اصفهان, 2010 Background: Adequate fetal movement is one of health markers and can be altered under influence of pathologic and nonpathologic causes. Since, glucose is an energetic agent, and its availability for central nervous system (CNS) provides better ...
Nasrin Sarafraz +3 more
doaj
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
In their investigation of Hudson Canyon sediments, students will discover how sediment size is related to the amount of time the sediment is suspended in water.
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Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Water Alternatives, 2021 Many new dam projects are presently being put forward, revealing both the comeback of large hydraulic infrastructure and the resilience of the modern ontology of water. To contribute to the understanding of modern water’s perpetuation, this paper takes a
Silvia Flaminio
doaj
Mass movement in Tangoio conservation reserve northern Hawkes Bay [PDF]
, 1971 In a random sample of 52 valley-side profiles at Tangoio, mass movements are shown to occur preferentially on profiles with a northerly aspect, which are long, or steeply sloping.
Eyles, R.J.
core +1 more source