Results 121 to 130 of about 15,364,286 (297)
Water in the 2006 Virginia General Assembly
, 2006 The 2006 Virginia General Assembly convened January 11 and adjourned March 11, with a reconvened (“veto”) session on April 19. The legislature considered 3287 measures; among the most important business was development of the biennial state budget. Below
Virginia Water Resources Research Center
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Water-Related Bills in the 2008 Virginia General Assembly
, 2008 The 2008 Virginia General Assembly session opened January 9 and adjourned March 13. Work on the biennial state budget required a few additional days beyond the scheduled adjournment date of March 8.
Virginia Water Resources Research Center
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Macromolecular condensation buffers intracellular water potential. [PDF]
Nature, 2023 Watson JL +30 more
europepmc +1 more source
Water in the 2001 General Assembly
, 2001 The 2001 Virginia General Assembly lasted from January 10 to February 24. The House of Delegates and Senate considered 2645 bills and resolutions. By our reckoning, 123 of these had something to do with water resources or water-related activities.
Virginia Water Resources Research Center
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The Volume of Water Bills in the 1999 Virginia General Assembly
, 1999 The Virginia General Assembly held its 1999 session from January 13 to February 27. During the regular session, lawmakers considered 2,735 bills and resolutions, compared to 2945 measures considered in the longer 1998 session.
Virginia Water Resources Research Center
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
1998 General Assembly Legislation Related to Water
, 1998 The Virginia General Assembly held its regular session from January 14 to March 17, then reconvened April 22-23 to respond to the governor’s vetoes.
Manfre, Joseph +1 more
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