Results 131 to 140 of about 6,486,648 (282)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Exploring aquaporin functions during changes in leaf water potential. [PDF]

open access: yesFront Plant Sci, 2023
Byrt CS   +5 more
europepmc   +1 more source

POTENTIAL WATER USE CONFLICTS GENERATED BY IRRIGATED AGRICULTURE IN RHODE ISLAND [PDF]

open access: yes
This study constructs a simulation model to evaluate the potential for conflict among residential and agricultural users of water in southern Rhode Island.
Gold, Arthur   +3 more
core   +1 more source

The pattern of soil water extraction by individual kiwifruit vines : a thesis presented in partial fulfillment of the requirements for the Master of Agricultural Science in Soil Science at Massey University [PDF]

open access: yes, 1987
In order to efficiently design and operate irrigation systems water balance studies are needed. To date few of these studies have been carried out on kiwifruit. Detailed measurements of water extraction were made beneath two 7 year old kiwifruit vines.
Snow, Valerie Olga
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Improving the Catchment through Market Based Instruments [PDF]

open access: yes
In this paper, six potential MBIs are discussed that have potential for improving environmental outcomes.Australia;water;urban water;market based ...
Darla Hatton MacDonald
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Technology transfer potential of an automated water monitoring system [PDF]

open access: yes
The nature and characteristics of the potential economic need (markets) for a highly integrated water quality monitoring system were investigated. The technological, institutional and marketing factors that would influence the transfer and adoption of an
Eischen, M. A.   +3 more
core   +1 more source

Water Retention, Bulk Density, Particle Size, and Thermal and Hydraulic Conductivity of Arable Soils in Interior Alaska [PDF]

open access: yes, 1990
The relative proportion of liquid, gas, and solid as constituents of soil depends on factors such as climate, biological activity, and management practices.
Sharratt, Brenton S.
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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