Results 61 to 70 of about 6,486,648 (282)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Deficit irrigation scheduling is becoming increasingly important under commercial conditions. Water status measurement is a useful tool in these conditions. However, the information about water stress levels for olive trees is scarce.
María José Martín-Palomo +7 more
doaj +1 more source
An alternative view on the Bateman-Luke variational principle [PDF]
A new derivation of the Bernoulli equation for water waves in three-dimensional rotating and translating coordinate systems is given. An alternative view on the Bateman-Luke variational principle is presented.
Ardakani, Hamid Alemi
core +2 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Indirect evidence for genetic differentiation in vulnerability to embolism in Pinus halepensis
Climate change is increasing mean temperatures and in the eastern Mediterranean is expected to decrease annual precipitation. The resulting increase in aridity may be too rapid for adaptation of tree species unless their gene pool already possesses ...
Rakefet eDavid-Schwartz +9 more
doaj +1 more source
Influences of chloride immersion on zeta potential and chloride in concentration of cement-based materials [PDF]
In this paper, the zeta potential of freshly mixed cement paste and hardened cement pastes, as well as the concentration index, was measured. The influences of chloride concentration in mixing water and slag content on zeta potential of freshly mixed ...
De Schutter, Geert +2 more
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Trade-offs Between Water Transport Capacity and Drought Resistance in Neotropical Canopy Liana and Tree Species [PDF]
In tropical forest canopies, it is critical for upper shoots to efficiently provide water to leaves for physiological function while safely preventing loss of hydraulic conductivity due to cavitation during periods of soil water deficit or high ...
De Guzman, Mark E. +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

