Results 121 to 130 of about 18,853,489 (341)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The effects of water quality on freshwater fish populations - final report [PDF]
, 1990 There is a need to determine quantitative relationships between fishery status and water quality in order to make informed judgements concerning fishery health and the setting of environmental quality standards for fishery protection.
Gulson, J., Mainstone, C.P.
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
BMC ChemistryThe single-stage floating catalyst chemical vapor deposition (SS-FCCVD) method using the ferrocene route (e.g., ferrocene: catalyst and camphor: carbon source) offers significant but largely unexplored versatility for the production of carbon nanotubes ...
B. V.N. Sewwandi +5 more
doaj +1 more source
Effects of Water Released From Stratified and Unstratified Reservoirs on the Downstream Water Quality [PDF]
, 1982 Water quality samples were collected from the Little River system in Pine Creek Lake, Oklahoma, and Gillham Lake, Arkansas, and their associated tailwaters during the winter (reservoirs unstratified) and summer (reservoirs stratified) of 1980. Downstream
Smith, Stephen B.
core +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Next NanotechnologyIn the realm of nanotechnology, carbon-based materials stand as a testament to how nature's simplest element can inspire boundless innovation. However, challenges including defect-free synthesis, high production costs, purification or separation ...
Aruna Yadav +5 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Water Quality: Improving Water Quality Utilizing Hemp [PDF]
Journal of Agriculture and Environmental Sciences, 2017 Michael D. McDermott, William D. Strait
openaire +1 more source
, 2003 The Town of Exeter was interested in creating an education program for nonpoint source pollution. Exeter was not designated as a small municipal separate storm sewer system (MS4) with the first group of Seacoast towns, but realized we had some of the ...
Duffy, Phyllis E.
core +2 more sources