Results 91 to 100 of about 15,051,160 (301)

2008 New Jersey Integrated Water Quality Monitoring and Assessment Report

open access: yes, 2009
The 2008 New Jersey Integrated Water Quality Monitoring and Assessment Report (Integrated Report) provides extensive information about the water quality conditions and trends of New Jersey’s water resources to inform the general public and guide water ...
New Jersey. Department of Environmental Protection. Bureau of Water Quality Standards and Assessment
core  

Water Quality Assessment and Trophic State Evaluation of Foy’s Lake, Bangladesh

open access: yesJournal of Agroforestry and Environment
In recent years, human activities have significantly altered Foy's Lake, shifting it from a clear, pristine state to a turbid, eutrophic condition. Thus, this study analyzed seasonal variations of physicochemical parameters, chlorophyll-a levels, and the
Md. Humayun Kabir, Partho Saha
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

An Enzyme Immunoassay Developed for the Determination of Methylene Blue in Aquatic Products Based on a Novel Hapten

open access: yesChemosensors
Methylene blue (MB) is a chemical dye which is used as an alternative drug for malachite green. In this study, based on computational chemistry, a novel hapten (TM) of MB was designed by comparing the conformational and electronic properties of MB.
Xuanyun Huang   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

QUALITY ASSESSMENT OF DRINKING WATER FROM DIFFERENT WATER SUPPLY SOURCES IN VYNNYKY (LVIV REGION)

open access: yesEnvironmental Problems
A thorough evaluation of drinking water quality was performed for several sources in Vynnyky, Lviv region, including springs on B. Khmelnytsky and M. Kypriyan Streets, a well located at 17 K. Hrynevycheva Street, and tap water from the centralized supply
Ulyana Khromyak   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Environmental microbiome diversity and stability is a barrier to antimicrobial resistance gene accumulation

open access: yesCommunications Biology
When antimicrobial resistant bacteria (ARB) and genes (ARGs) reach novel habitats, they can become part of the habitat’s microbiome in the long term if they are able to overcome the habitat’s biotic resilience towards immigration.
Uli Klümper   +23 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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