Results 51 to 60 of about 429,250 (301)

Assessment of Çinarli Stream (Hafik -Sivas)'S Water Quality via Physico-Chemical Methods

Turkish Journal of Agriculture: Food Science and Technology, 2016
Çınarlı Stream within the borders of Hafik district of Sivas city is famous for its natural beauties and rich water resource. By passing through a steep valley, Çınarlı stream reaches at forages exhibiting gypsum characteristic of Çınarlı Village.
Ekrem Mutlu, Banu Kutlu, Tuğba Demir
doaj   +1 more source

Progress in the Research of the Toxicity Effect Mechanisms of Heavy Metals on Freshwater Organisms and Their Water Quality Criteria in China

Journal of Chemistry, 2020
Water quality criteria are the scientific basis for formulating water quality standards and environmental management practices. Due to the development of urbanization and industrialization, the problem of heavy metal pollution has become a serious ...
Ya-jun Hong, Wei Liao, Zhen-fei Yan, Ying-chen Bai, Cheng-lian Feng, Zu-xin Xu, Da-yong Xu   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Water quality criteria for livestock watering – a comparison among different regulations

Acta Scientiarum: Animal Sciences, 2014
This review presents water quality criteria for livestock adopted by different countries/states and discusses how those limit values are established. The method used was a literature data survey, available in the electronic pages of regulatory agencies ...
Simone Valente-Campos, Elizabeth de Souza Nascimento, Gisela de Aragão Umbuzeiro   +2 more
doaj   +1 more source

Mapping the potential for Payments for Ecosystem Services schemes to improve water quality in agricultural catchments: A multi-criteria approach based on the supply and demand concept

, 2021
Payments for Ecosystem Services (PES) schemes are an increasingly popular form of catchment management for improving surface water and groundwater quality.
Roberts, William M., Couldrick, Laurence B., Couldrick, L. B., Williams, G., Robins, Dawn, Robins, D., Roberts, W., Williams, Gareth, Cooper, David, Cooper, D.   +9 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Emerging Contaminants in the Effluent of Wastewater Should Be Regulated: Which and to What Extent?

Toxics
Effluent discharged from urban wastewater treatment plants (WWTPs) is a major source of emerging contaminants (ECs) requiring effective regulation. To this end, we collected discharge datasets of pharmaceuticals (PHACs) and endocrine-disrupting chemicals
Weiwei Yang, Qingwei Bu, Qianhui Shi, Ruiqing Zhao, Haitao Huang, Lei Yang, Jianfeng Tang, Yuning Ma   +7 more
doaj   +1 more source

The effects of nutrients on stream invertebrates: a regional estimation by generalized propensity score

Ecological Processes, 2018
Introduction The effects of nutrients on stream conditions within individual streams or small areas have been studied extensively, but the same effects over a large region have rarely been examined due to the difficulty of applying large-scale ...
Zutao Ouyang, Song S. Qian, Richard Becker, Jiquan Chen   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source