Results 171 to 180 of about 1,680,919 (308)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Water quality index and human health risk analysis in urban drinking water sources. [PDF]

Sci Rep
Nasim I, Nawaz R, Farwa A, Ahmad S, Irshad MA, Al-Hussain SA, Irfan A, Zaki MEA.   +7 more
europepmc   +1 more source

Integrated approach to hydrogeochemical appraisal of groundwater quality concerning arsenic contamination and its suitability analysis for drinking purposes using water quality index. [PDF]

Sci Rep, 2023
Ullah Z, Zeng XC, Rashid A, Ghani J, Ali A, Shah M, Zainab R, Almutairi MH, Sayed AA, Aleya L.   +9 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Integrated evaluation of groundwater irrigation suitability using hydrochemical indices and irrigation water quality index (IWQI) in Aksum, Tigray, Ethiopia. [PDF]

Sci Rep
Ataklti B, Tesema FW, Berhe BA.
europepmc   +1 more source

Water quality index, ecotoxicology and human health risk modelling of surface and groundwater along illegal crude oil refining sites in a developing economy. [PDF]

Heliyon, 2023
Azuamah KO, Appiah-Effah E, Akodwaa-Boadi K.   +2 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Water quality index prediction via a robust machine learning model using oxygen-related indices for river water quality monitoring. [PDF]

Sci Rep
Arzhangi A, Partani S.
europepmc   +1 more source

Evaluation of water quality index and geochemical characteristics of surfacewater from Tawang India. [PDF]

Sci Rep, 2022
Gaur N, Sarkar A, Dutta D, Gogoi BJ, Dubey R, Dwivedi SK.   +5 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source