Results 181 to 190 of about 489,039 (311)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Integrated evaluation of groundwater irrigation suitability using hydrochemical indices and irrigation water quality index (IWQI) in Aksum, Tigray, Ethiopia. [PDF]

Sci Rep
Ataklti B, Tesema FW, Berhe BA.
europepmc   +1 more source

Water quality index, ecotoxicology and human health risk modelling of surface and groundwater along illegal crude oil refining sites in a developing economy. [PDF]

Heliyon, 2023
Azuamah KO, Appiah-Effah E, Akodwaa-Boadi K.   +2 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Water quality index prediction via a robust machine learning model using oxygen-related indices for river water quality monitoring. [PDF]

Sci Rep
Arzhangi A, Partani S.
europepmc   +1 more source

Evaluation of water quality index and geochemical characteristics of surfacewater from Tawang India. [PDF]

Sci Rep, 2022
Gaur N, Sarkar A, Dutta D, Gogoi BJ, Dubey R, Dwivedi SK.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Kernel principal component analysis-based water quality index modelling for coastal aquifers in Saudi Arabia. [PDF]

Sci Rep
Aldrees A, Jibrin AM, Dan'azumi S, Al-Suwaiyan M, Abba SI, Yaseen ZM.   +5 more
europepmc   +1 more source

Water quality index assessment methods for surface water: A case study of the Citarum River in Indonesia. [PDF]

Heliyon, 2022
Marselina M, Wibowo F, Mushfiroh A.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source