Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Water quality index prediction via a robust machine learning model using oxygen-related indices for river water quality monitoring. [PDF]
Sci RepArzhangi A, Partani S.
europepmc +1 more source
Evaluation of water quality index and geochemical characteristics of surfacewater from Tawang India. [PDF]
Sci Rep, 2022 Gaur N +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Kernel principal component analysis-based water quality index modelling for coastal aquifers in Saudi Arabia. [PDF]
Sci RepAldrees A +5 more
europepmc +1 more source
Water quality index assessment methods for surface water: A case study of the Citarum River in Indonesia. [PDF]
Heliyon, 2022 Marselina M, Wibowo F, Mushfiroh A.
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Water quality index assessment of toxicity in direct and roofs runoff rainwater in industrial and remote areas of Eastern Nigeria. [PDF]
Sci RepNicholas ES, Okudo CC, Ukoha PO.
europepmc +1 more source
Probabilistic risk assessment and water quality index of a tropical delta river. [PDF]
PeerJ, 2021 Anani OA, Olomukoro JO.
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source