Results 201 to 210 of about 425,315 (313)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Determination of the Quality of Groundwater in Mankweng, Limpopo Province, South Africa, Using the Water Quality Index. [PDF]

open access: yesInt J Environ Res Public Health
Maliehe TS   +5 more
europepmc   +1 more source

Water Quality Index of Halda River, Southeastern Bangladesh

open access: green, 2020
Md. Safiqul Islam   +3 more
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Characterization of the surface water of a municipal natural park by quality indexes

open access: diamond, 2019
Thayna Suane Polheim   +2 more
openalex   +2 more sources

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