Results 91 to 100 of about 23,988,377 (298)

Performance indicators model assessment for water system quality and supply in Montenegro [PDF]

open access: yesJournal of the Serbian Chemical Society
The paper researches water quality, supply and management system assessment problems of the Montenegrin costal region. A significant problem is generated by seasonal tourism, the main branch of Montenegrin costal economy.
Doklestić Olivera   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

401 Water quality certification

open access: yes
Water Boards Water Boards KRI STINE MURRAY, CHAIR I JAYNE J o y, EXECUTIVE OFFICER e GAVIN N EWSOM GOVfA NOR YANA GARCIA SECRETARY FOR ENVIRONMENTAL PROTECTION 3737 Main Street, Suite 500, Riverside, CA 92501-3348 I www.waterboards.ca.gov/santaana Santa ...
California Regional Water Quality Control Board;
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Modelling water quality for water distribution systems [PDF]

open access: yes, 1999
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Maintaining water quality in distribution systems has become a prominent issue in the study of water networks.
Maier, Stefan Heinrich
core   +4 more sources

Evaluation of a developed Water Quality Monitoring System (WQMS) alongside arithmetic water quality index model

open access: yesJournal of Environmental Engineering and Landscape Management
Measurement of the quality of water before usage is important; however, this is challenging in developing countries, where water testing equipment is expensive and inaccessible. A Water Quality Monitoring System (WQMS) was developed to ease these unsafe
Eganoosi Esme Atojunere   +1 more
doaj   +1 more source

A multidisciplinary approach for evaluating spatial and temporal variations in water quality

open access: yes, 2019
The primary goal of this study is to investigate the classification capability of several artificial intelligence techniques, including the decision tree (DT), multilayer perceptron (MLP) network, Naïve Bayes, radial basis function (RBF) network, and ...
Dung, Tran Duc   +13 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

2004 Texas Water Quality Inventory [PDF]

open access: yes, 2004
Waller Creek Working ...
Texas Commission on Environmental Quality
core   +1 more source

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