Results 111 to 120 of about 23,988,377 (298)

Numerical Simulations of Water Quality Measurement Model in an Opened-Closed Reservoir with Contaminant Removal Mechanism

International Journal of Differential Equations, 2018
The mathematical simulation of water contaminant measurement is often used to assess the water quality. The monitoring point placement for water quality measurement in an opened-closed reservoir can give accurate or inaccurate assessment.
Kaboon Thongtha, Jaipong Kasemsuwan
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Tehran Water Quality Assessment Using DPSIR Model

علوم آب و خاک, 2018
Since the introduction of cities and urbanization, healthy water supplement and urban wastewater treatment have been considered as an important factor to evaluate progress in the urban areas. Tehran as a megacity is facing the lack of water. Tehran water
H. Sarmadi, E. Salehi, L. Zebardast, M. Aghababaei   +3 more
doaj  

An optimized ensemble ML-WQI model for reliable water quality prediction by minimizing the eclipsing and ambiguity issues

Applied Water Science
Monitoring water quality is essential for the sustenance of the ecosystem and various forms of life on Earth. The water quality index (WQI) models are the widely adopted approach to water quality monitoring.
Ashifur Rahman, M. M. Mahbubul Syeed, Md. Rajaul Karim, Kaniz Fatema, Razib Hayat Khan, Mohammad Faisal Uddin   +5 more
doaj   +1 more source

A Conflict Resolution Model for Water Allocation and River Water Quality Management [PDF]

آب و فاضلاب, 2007
In this study, a conflict resolution methodology for water quality management in a river system is presented. The proposed model maximizes an objective function based on the Nash product which includes different utility functions related to the water ...
Ali Moridi, Mohammad Karamouz
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Towards benchmarking an in-stream water quality model [PDF]

Hydrology and Earth System Sciences, 2007
A method of model evaluation is presented which utilises a comparison with a benchmark model. The proposed benchmarking concept is one that can be applied to many hydrological models but, in this instance, is implemented in the context of an in-stream ...
doaj  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

ICPO-ACNN-BiGRU-CA: High-Precision Water Quality Prediction Model for Mariculture

Journal of Marine Science and Engineering
Accurate water quality prediction is crucial for the sustainable management of mariculture, yet it faces challenges in modeling high-dimensional nonlinear data and optimizing model hyperparameters efficiently. To address this, a novel deep learning model
Hongqian Wu, Wenjing Liu, Zhenhua Li
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source