Results 41 to 50 of about 834,737 (262)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Computer model improves real-time management of water quality

open access: yesCalifornia Agriculture, 1997
Members of the San Joaquin River Management Program's Water Quality Subcommittee have developed a water-quality forecasting model to help improve the timing, coordination and management of agricultural drainage and reservoir releases ...
Nigel W.T. Quinn   +4 more
doaj   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Aquaculture 4.0: hybrid neural network multivariate water quality parameters forecasting model

open access: yesScientific Reports, 2023
This study examined the efficiency of hybrid deep neural network and multivariate water quality forecasting model in aquaculture ecosystem. Accurate forecasting of critical water quality parameters can allow for timely identification of possible problem ...
Elias Eze   +3 more
doaj   +1 more source

AIQUAM: Artificial Intelligence-based water QUAlity Model

open access: yes2022 IEEE 18th International Conference on e-Science (e-Science), 2022
Monitoring the impact of the pollutants on the sea is a crucial issue for coastal human activities, such as aquaculture. However, leveraging a continuous microbiological laboratory analysis is unfeasible for costs and practical reasons. Fish and mussel farms are critically sensitive to seawater quality and thus require continuous monitoring to enforce ...
De Vita, Ciro Giuseppe   +5 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Water Quality Coupling Model Classifications and Their Applications

open access: yesRenmin Zhujiang, 2020
Water quality model is widely used in water quality simulation, prediction and auxiliarydecision-making, which is an important tool to study water pollution and control waterenvironment.
WANG Wei, WANG Xiaoqing
doaj  

Aquaculture Prediction Model Based on Improved Water Quality Parameter Data Prediction Algorithm under the Background of Big Data

open access: yesJournal of Applied Mathematics, 2022
Computer science and technology under the background of big data are closely related to the development of modern agriculture. The application of information processing technology in aquaculture will promote the scientific development of aquaculture. The
Yuan Jiang, Fei Yan
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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