Results 81 to 90 of about 1,634,989 (241)
Gender in Water and Sanitation [PDF]
, 2010 The report highlights the experiences of mainstreaming gender at various levels in the water and sanitation sector. It begins with a discussion on gender responses to policy and its requirement for analysis and clear policy objectives to guide operations.
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The green and blue crop water requirement WATNEEDS model and its global gridded outputs. [PDF]
Sci Data, 2020 Chiarelli DD +5 more
europepmc +1 more source
Quality of Refill Drinking Water in Greater Jakarta in 2010 [PDF]
, 2011 Background: Drinking water is increasingly scarce in urban areas. Water consumed by the public must meet the requirements of safe drinking water quality for health. Many people use refill drinking water to meet the needs of drinking water daily.
Kurniatri, A. A. (Arifayu)
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Water requirement and growth indicators of forest tree species seedlings produced with automated irrigation management. [PDF]
PLoS One, 2020 Bueno MM +4 more
europepmc +1 more source
Pesticides and metabolites in groundwater: examples from two major UK aquifers [PDF]
, 2007 Reducing the impact of anthropogenic pollution on groundwater bodies and ameliorating any deterioration of water quality is central to key legislative drivers such as the EU Water Framework Directive and the proposed daughter Directive relating to the ...
Chilton, P.J. +4 more
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source