Results 81 to 90 of about 375,469 (313)

Santa Clara Valley Water District Floodplain Mailer

open access: yes, 2013
Special permits required in floodplains Construction within a FEMA designated floodplain may have special permit requirements from your local municipality. Contact your community’s building department for more information before you build, grade or fill.
Santa Clara Valley Water District;
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Composite water management index: a tool for water management [PDF]

open access: yes, 2018
"India is suffering from the worst water crisis in its history and millions of lives and livelihoods are under threat. Currently, 600 million Indians face high to extreme water stress and about two lakh people die every year due to inadequate access to ...
NITI Aayog, Government of India
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

AN ASSESSMENT OF THE CROP WATER DEMAND AND IRRIGATION WATER SUPPLY AT PABBI MINOR OF WARSAK GRAVITY CANAL [PDF]

open access: yes
The research study was conducted on irrigation water supply and demand at Pabbi minor of Warsak gravity canal from June to August 1998. Objectives of the research were to assess the actual supply of irrigation water, irrigation water demand of major ...
Ehsan Inam Ullah   +2 more
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Ecological Water Requirement of Natural Vegetation in the Tarim River Basin Based on Multi-Source Data

open access: yes
The Tarim River Basin is one of the most ecologically fragile regions around the world in the arid areas of Northwest China. The study of natural vegetation ecological water requirement (EWR) is the basis for the promotion of regional ecological ...
Shikang Zhao   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Investigations of stream-aquifer interactions using a coupled surface-water and ground-water flow model

open access: yes, 1997
A finite element numerical model is developed for the modeling of coupled surface-water flow and ground-water flow. The mathematical treatment of subsurface flows follows the confined aquifer theory or the classical Dupuit approximation for unconfined ...
Maddock, Thomas, III   +2 more
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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