Results 51 to 60 of about 1,201,661 (315)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
, 2010 A new series of high speed hard chine planing hulls was designed to study their performance in both calm water and waves. This study was undertaken to determine the influence of hull design parameters such as length-displacement ratio, static trim angle ...
Taunton, D.J. +2 more
core +1 more source
, 2021 The physiological mechanisms underlying drought responses are poorly documented in mangroves, which experience nearly constant exposure to saline water. We measured gas exchange, foliar abscisic acid (ABA) concentration, and vulnerability to embolism in ...
Huai-Tong Si +7 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Antimicrobial Resistance of Heterotrophic Bacteria in Drinking Water-Associated Biofilms
, 2022 Antimicrobial resistance (AMR) is one of the major threats to human health and is becoming an environmental challenge for water resources too. Our study’s aim was: to assess the AMR of heterotrophic bacteria in drinking water-associated biofilms ...
Zvezdimira Tsvetanova +2 more
core +1 more source
e-PolymersWith the depletion of energy and the increasing awareness of environmental protection, bio-polymer films will become a possible alternative to plastic packaging in the future.
Yang Xueying, Tian Weiyu, Yu Huanyang
doaj +1 more source
Prospects for Evaluating the Damageability of Asphalt Concrete Pavements During Cold Recycling
The Baltic Journal of Road and Bridge Engineering, 2020 The article considers improvement of the methodology for accounting for the degradation of asphalt concrete working in the upper layers of the pavement. Development of recycling technologies for road structures is an ongoing process; it allows reaching a
Vitali Zankavich +7 more
doaj +1 more source
Detection of antibiotic-resistant bacteria and their resistance genes in wastewater, surface water, and drinking water biofilms [PDF]
FEMS Microbiology Ecology, 2003 Abstract In view of the increasing interest in the possible role played by hospital and municipal wastewater systems in the selection of antibiotic-resistant bacteria, biofilms were investigated using enterococci, staphylococci, Enterobacteriaceae, and heterotrophic bacteria as indicator organisms.
Schwartz, T. +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source