Results 171 to 180 of about 1,209,524 (216)

On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?

open access: yesAdvanced Therapeutics, EarlyView.
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley   +1 more source

Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings

open access: yesAdvanced Therapeutics, EarlyView.
Bacterial cellulose (BC)‐based wound dressings combine high water retention, biocompatibility, and mechanical strength to support wound healing. This review highlights advanced functionalization strategies and fabrication techniques that enhance BC's therapeutic performance, establishing it as a promising material for next‐generation wound care ...
Elif Naz Gürsoy   +4 more
wiley   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

open access: yesAdvanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak   +2 more
wiley   +1 more source

Underground well water level observation grid dataset from 2005 to 2022. [PDF]

open access: yesSci Data
Wang M   +12 more
europepmc   +1 more source

Exploration of Half‐Cycle Length of Converging Circular Wavy Duct with Diverging‐Outlet: Turbulent Water Dynamics

open access: yesAdvanced Theory and Simulations, EarlyView.
Increasing half‐cycles intensifies turbulence due to enhanced vortex interactions and flow separation at the diverged‐outlets. Longer wavy ducts are shown to increase flow acceleration, resulting in greater output velocities and more turbulent‐kinetic‐energy production. Wave‐period plays a crucial role in determining turbulent intensity, with amplitude
I. L. Animasaun   +2 more
wiley   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

open access: yesAdvanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang   +14 more
wiley   +1 more source

Accessible water quality monitoring through hybrid human-machine colorimetric methods. [PDF]

open access: yesEnviron Monit Assess
McCarty DA   +7 more
europepmc   +1 more source

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