On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley +1 more source
Industrial water consumption efficiency and driving factors based on the super-efficient SBM and Tobit approach. [PDF]
Duo H+7 more
europepmc +1 more source
Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings
Bacterial cellulose (BC)‐based wound dressings combine high water retention, biocompatibility, and mechanical strength to support wound healing. This review highlights advanced functionalization strategies and fabrication techniques that enhance BC's therapeutic performance, establishing it as a promising material for next‐generation wound care ...
Elif Naz Gürsoy+4 more
wiley +1 more source
Study on the dynamic prediction and optimum regulation scheme of water resource carrying capacity in the yellow river basin. [PDF]
Zhou K.
europepmc +1 more source
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak+2 more
wiley +1 more source
Underground well water level observation grid dataset from 2005 to 2022. [PDF]
Wang M+12 more
europepmc +1 more source
Increasing half‐cycles intensifies turbulence due to enhanced vortex interactions and flow separation at the diverged‐outlets. Longer wavy ducts are shown to increase flow acceleration, resulting in greater output velocities and more turbulent‐kinetic‐energy production. Wave‐period plays a crucial role in determining turbulent intensity, with amplitude
I. L. Animasaun+2 more
wiley +1 more source
Exploring the driving mechanism path of ecosystem service relationships based on the social-ecological system framework. [PDF]
Zhang Y+5 more
europepmc +1 more source
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang+14 more
wiley +1 more source
Accessible water quality monitoring through hybrid human-machine colorimetric methods. [PDF]
McCarty DA+7 more
europepmc +1 more source