Results 81 to 90 of about 11,682,067 (381)
When Elbridge Gerry, a native son of Marblehead, Massachusetts, affixed a signature to the declaration of Independence, Boston had only about 16,000 inhabitants. Not only has Boston grown to over 40 times that size, but there are more peole in Metropolitan Boston now than there were in all thirteen colonies in 1776. Not only has our nation grown almost
openaire +3 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
The control of irrigation volume is of significant importance in arid regions of northwest China. Particularly, it has a crucial impact on the salinization of shallow groundwater areas.
Changfu Tong+3 more
doaj +1 more source
A Transdisciplinary Review of Deep Learning Research and Its Relevance for Water Resources Scientists [PDF]
Deep learning (DL), a new generation of artificial neural network research, has transformed industries, daily lives, and various scientific disciplines in recent years. DL represents significant progress in the ability of neural networks to automatically
Chaopeng Shen
semanticscholar +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
The natural support capacity (NSC) of water resources is a key aspect of the regional carrying capacity of water resources, and it can reflect the quality and quantity of water resources in a region. This paper aims to evaluate the NSC of water resources
Feifeng Cao+3 more
semanticscholar +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Simulation of Maize Growth Under the Applications of Brackish Water in Northwest China
The objective of this study is to assess the suitability of the AquaCrop model for growing maize using brackish water irrigation in Northwest China. Additionally, this study aims to examine how maize utilizes water in various soil layers when irrigated ...
Changfu Tong+3 more
doaj +1 more source