Results 61 to 70 of about 1,035,406 (257)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Water Demand Forecast in the Baiyangdian Basin with the Extensive and Low-Carbon Economic Modes

Journal of Applied Mathematics, 2014
The extensive and low-carbon economic modes were constructed on the basis of population, urbanization level, economic growth rate, industrial structure, industrial scale, and ecoenvironmental water requirement.
T. L. Qin, D. H. Yan, G. Wang, J. Yin
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Study of Drought Characteristics and Atmospheric Circulation Mechanisms via a “Cloud Model”, Inner Mongolia Autonomous Region, China

Agronomy
Droughts are long-term natural disasters and encompass many unknown factors. Herein, yearly and seasonal standardized precipitation evapotranspiration index (SPEI) values were calculated by analyzing monthly temperature and precipitation data from 1971 ...
Sinan Wang, Henglu Miao, Yingjie Wu, Wei Li, Mingyang Li   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

TCN-Attention Model-Based Prediction of Reference Crop Evapotranspiration in Northern Henan Province

Agronomy
Accurate and reliable estimation of reference crop evapotranspiration (ET0) in the North Henan Plain is crucial for agricultural water resource management, production, and food supply in China. This study aims to evaluate the performance of deep learning
Jianqin Ma, Fu Zhao, Bifeng Cui, Lei Liu, Xiuping Hao, Yan Zhao, Yu Ding, Yijian Chen   +7 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

[Groundwater monitoring and the POA ACQUACENTRO projects - state of the art and future perspectives in Lazio]

Acque Sotterranee
[Article in Italian] La gestione sostenibile delle risorse idriche rappresenta una delle principali sfide globali contemporanee, in virtù del ruolo essenziale dell’acqua dolce quale risorsa indispensabile per il sostentamento della vita e il ...
Roberto Ceccarini, Alessandra Scala, Emanuele Bernini, Camilla Ciotti, Annalaura Rossi, Eliana Barra, Cristina Venezia, Adele Clausi, Alberto Di Ludovico, Marco Le Foche   +9 more
doaj   +1 more source