Results 41 to 50 of about 1,277,146 (271)

Predicting salinity levels in the Mekong delta (Viet Nam): analysis of machine learning and deep learning models

open access: yesDiscover Artificial Intelligence
Salinity intrusion stands out as a severe yet escalating challenge facing the water resource management and agricultural production of the Mekong Delta in Vietnam as a result of climate change and upstream hydrological changes.
Phong Nguyen Duc   +4 more
doaj   +1 more source

Water resources allocation based on water resources supply-demand forecast and comprehensive values of water resources

open access: yesJournal of Hydrology: Regional Studies, 2023
Study region: The Yellow River Basin (YRB) in China. Study focus: The water resources supply-demand imbalance hinders sustainable socioeconomic development, which can be effectively addressed by the water resources allocation (WRA).
Fengyi Zhang   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

An efficient parallel runoff forecasting model for capturing global and local feature information

open access: yesScientific Reports
Artificial intelligence has significantly accelerated the development of hydrological forecasting. However, research on how to efficiently identify the physical characteristics of runoff sequences and develop forecasting models that simultaneously ...
Yang-hao Hong   +5 more
doaj   +1 more source

Stability Assessment of Hesigewula Open-pit Coal Mine Based on Geomorphic Information Entropy of Watershed System

open access: yesShuitu baochi tongbao, 2023
[Objective] The stability evaluation of an open-pit mining area was carried out in order to provide technical support for landform remodeling, ecological environment restoration, and soil erosion monitoring in a mining area.
Zhao Shuixia   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A deep learning runoff prediction model based on wavelet decomposition and dynamic feature fusion

open access: yesScientific Reports
To address the stochasticity, time-varying characteristics, and nonlinear dynamics of runoff series, this research proposes a novel deep learning architecture, BWDformer, based on wavelet decomposition and dynamic feature fusion, to enhance the precision
Dong-mei Xu   +5 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Spatiotemporal Variation in Understory Litter Coverage Based on Multi-Angle Remote Sensing Inversion Using Sentinel-2 and MODIS BRDF Imagery

open access: yesRemote Sensing
The forest understory litter fraction (FVCy) is a critical indicator for evaluating the effectiveness of “understory erosion” control in red soil regions; however, its high-precision, large-scale monitoring remains challenging due to canopy occlusion ...
Zhujun Gu   +9 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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