Results 31 to 40 of about 3,684,192 (295)

An efficient parallel runoff forecasting model for capturing global and local feature information

open access: yesScientific Reports
Artificial intelligence has significantly accelerated the development of hydrological forecasting. However, research on how to efficiently identify the physical characteristics of runoff sequences and develop forecasting models that simultaneously ...
Yang-hao Hong   +5 more
doaj   +1 more source

Stability Assessment of Hesigewula Open-pit Coal Mine Based on Geomorphic Information Entropy of Watershed System

open access: yesShuitu baochi tongbao, 2023
[Objective] The stability evaluation of an open-pit mining area was carried out in order to provide technical support for landform remodeling, ecological environment restoration, and soil erosion monitoring in a mining area.
Zhao Shuixia   +6 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

An Evaluation of the Effects of Dredging Within the Arkansas River Navigation System - Volume I - Introduction, Summary and Conclusions, and Recommendations [PDF]

open access: yes, 1978
The foundation for the development of the Arkansas River was laid with the authorization of many upstream reservoirs in the comprehensive River and Harbor Act of 1946 signed by President Truman.
Research Center, Arkansas Water Resources
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Predicting salinity levels in the Mekong delta (Viet Nam): analysis of machine learning and deep learning models

open access: yesDiscover Artificial Intelligence
Salinity intrusion stands out as a severe yet escalating challenge facing the water resource management and agricultural production of the Mekong Delta in Vietnam as a result of climate change and upstream hydrological changes.
Phong Nguyen Duc   +4 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

A deep learning runoff prediction model based on wavelet decomposition and dynamic feature fusion

open access: yesScientific Reports
To address the stochasticity, time-varying characteristics, and nonlinear dynamics of runoff series, this research proposes a novel deep learning architecture, BWDformer, based on wavelet decomposition and dynamic feature fusion, to enhance the precision
Dong-mei Xu   +5 more
doaj   +1 more source

Spatiotemporal Variation in Understory Litter Coverage Based on Multi-Angle Remote Sensing Inversion Using Sentinel-2 and MODIS BRDF Imagery

open access: yesRemote Sensing
The forest understory litter fraction (FVCy) is a critical indicator for evaluating the effectiveness of “understory erosion” control in red soil regions; however, its high-precision, large-scale monitoring remains challenging due to canopy occlusion ...
Zhujun Gu   +9 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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