Results 21 to 30 of about 1,035,406 (257)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Spatio-temporal characterization of drought variability in data-scarce regions using global precipitation data: a case study in Cauto river basin, Cuba

open access: yesScientific Reports
Drought is considered the most severe water-related disaster in the Cauto river basin, which is the longest river and the main agricultural producer in Cuba. Better understanding of drought characteristics is crucial to drought management.
Anh Phuong Tran   +7 more
doaj   +1 more source

Research on the homeostatic regulation of ecological fish tanks in human environment [PDF]

open access: yesE3S Web of Conferences
Indoor fish tanks have become an important device for enriching the home environment and improving indoor ecology. In order to investigate the ecological homeostatic regulation of fish tanks under the combination of traditional fish culture and modern ...
Li Leijing   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A synergistic framework integrating CPO-VMD with BiLSTM-TimesNet for accurate prediction of nonlinear and nonstationary runoff time series

open access: yesScientific Reports
Accurate runoff prediction is essential for effective water resource management, yet the complex characteristics of runoff sequences—such as nonlinearity, non-stationarity, and intricate temporal dependencies—pose significant challenges.
Dong-mei Xu   +6 more
doaj   +1 more source

A new experimental method to measure and calculate the tensile strength of concrete

open access: yesFrontiers in Materials, 2023
IntroductionA new method is introduced to test the tensile strength of concrete: the cylinder transverse splitting test. Compared with the cylinder splitting (or Brazilian) test, the cylinder transverse splitting test involves different load positions ...
Qihui Chai   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Risk Assessment of Yellow Muddy Water in High-Construction-Intensity Cities Based on the GIS Analytic Hierarchy Process Method: A Case Study of Guangzhou City

open access: yesLand
During urbanisation, extensive production and construction activities encroach on ecological spaces, leading to changes in environmental structures and soil erosion.
Xichun Jia   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

An efficient parallel runoff forecasting model for capturing global and local feature information

open access: yesScientific Reports
Artificial intelligence has significantly accelerated the development of hydrological forecasting. However, research on how to efficiently identify the physical characteristics of runoff sequences and develop forecasting models that simultaneously ...
Yang-hao Hong   +5 more
doaj   +1 more source

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