Results 61 to 70 of about 3,541,761 (309)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The effects of water quality on freshwater fish populations - final report [PDF]

open access: yes, 1990
There is a need to determine quantitative relationships between fishery status and water quality in order to make informed judgements concerning fishery health and the setting of environmental quality standards for fishery protection.
Gulson, J., Mainstone, C.P.
core  

Rain water harvesting management system in Zoo Negara, Selangor [PDF]

open access: yes, 2018
Water is a key requirement either to human, animal or plant. Rainwater Harvesting System (RWH) is a technology used to collect and store rainwater from the roof for reuse.
Md Yassin, Azlina   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Chicken Breast Meat Marinated with Increasing Levels of Sodium Bicarbonate

open access: yesThe Journal of Poultry Science, 2014
The aim of this study was to test the effect of different sodium bicarbonate concentrations on marination performances and meat quality properties. A total of 203 samples were obtained from an homogenous batch of 24 h post mortem chicken breast meat and
Massimiliano Petracci   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Does predawn water potential discern between irrigation treatments in Galician white grapevine cultivars?

open access: yesOENO One, 2014
Aims: To evaluate the usefulness of predawn water potential (Ψpd) to assess the water status of Galician grapevine cultivars for irrigation purposes. Methods and results: Three Galician white grapevine cultivars (Albariño, Godello and Treixadura) were ...
José Manuel Mirás-Avalos   +2 more
doaj   +1 more source

Evaluation of the effect of irrigation on biometric growth, physiological response and essential oil of Mentha spicata (L.) [PDF]

open access: yes, 2019
A field experiment was performed on spearmint (Mentha spicata L.) under different irrigation regimes in a hilly area of Southern Italy. Objectives of the study include evaluating the physiological and biometrical response of mint from plant ...
Ahmad, Uzair   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

"Terroir" effect, as a result of enviromental stess, depends more on soil depth than on soil type (Vitis vinifera L. cv. Grenache Noir, Côtes du Rhône, France, 2000)

open access: yesOENO One, 2006
Among other elements of the natural environment, soil greatly influences vine behaviour and berry composition. Its influence is complex, because soil affects vine water and mineral uptake, as well as temperature in the root zone.
Jacques Coipel   +3 more
doaj   +1 more source

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