Results 71 to 80 of about 1,674,802 (308)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Physiological Responses of Jatropha to Drought Stress in Coastal Sandy Land Conditions

open access: yesMakara Seri Sains, 2012
Jatropha curcas L., an important tropical biofuel crop, is reputed for its drought resistance, however, its ability to perform in dry conditions has still hardly been investigated.
Bambang Djadmo Kertonegoro   +4 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Validation of thermal indices for water status identification in grapevine

open access: yes, 2014
The use of thermal imaging represents a substantial progress in monitoring plant water status and therefore drought stress in field conditions. However, the effective use of thermal imaging requires consistent methods for data acquisition and image ...
Medrano, H. [0000-0002-6742-5746]   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Pullman Moscow Water Resources Committee Status Report

open access: yes, 1969
The report provides an update of the ground water supply in the Pullman Moscow basin, further development of the water resources of the basin, and the possible ...
Pullman Moscow Water Resources Committee
core  

Transgenic Tobacco with the BADH Gene Shows Enhanced Photosynthesis Resistance to Drought Stress Induced by PEG-6000

open access: yesAgronomy
Extreme weather events, including drought, have occurred worldwide with increasing frequency and severity in recent years. Drought stress is the main limiting factor for agricultural development in many regions, including tobacco—an important economic ...
Guiping Wang, Xinghong Yang, Xiaomin Xue
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Other title: online collection of publications by the Public Water Section of the Kansas Department of Health and Environment's Bureau of Water regarding the Capacity Development Program, 2000-2013

open access: yes, 2000
application/pdfReport on Findings on Improving the Technical, Financial and Managerial Capacity of Kansas' Public Water Systems by the Capacity Development Workgroup (2000) State of Kansas Capacity Development Strategy for Existing Public Water Supply ...
Kansas. Bureau of Water. Public Water Supply Section
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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