Results 91 to 100 of about 10,954,562 (237)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Arizona department of water resources: Securing Arizona\u27s water future

, 1998
The Arizona Department of Water Resources works to secure long-term dependable water supplies for Arizona\u27s communities. The Department: administers and enforces Arizona\u27s groundwater code, and surface water rights laws (except those related to ...
Arizona Department of Water Resources
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

“Hurdley technologies” utilized to improve postharvest life of asparagus spears (Asparagus officinalis L.)

Advances in Horticultural Science
Asparagus (Asparagus officinalis L.) has short shelf-life due to the high metabolic activity of the apical meristems. Storage at low temperature and high relative humidity is used commercially to keep fresh asparagus spears.
Martín Ernesto Tiznado-Hernández, Alfonso Antero Gardea-Bejar, Alberto Sánchez-Estrada, Jesús Antonio Orozco-Avitia, Angel Javier Ojeda-Contreras, Rosalba Troncoso-Rojas, Rodrigo Melendrez-Amavizca   +6 more
doaj   +1 more source

Other title: Kansas Municipal Water Conservation Plan Guidelines; Other title: Municipal Water Conservation Plan Guidelines

, 2007
application/pdf; "August 2007.", "Prepared cooperatively by: Kansas Water Office, Kansas Department of Agriculture, Division of Water Resources, Kansas Department of Health & Environment, Division Of Environment, Bureau of Water, [and] Kansas Rural ...
Kansas Water Office.
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Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Physiological and Biochemical Responses of ‘Burlat’ Sweet Cherry to Pre-Harvest Foliar Application of Calcium and Seaweed Extracts

Horticulturae
Sweet cherry (Prunus avium L.) is a highly valued fruit, and optimal nutrient management is crucial for enhancing yield and fruit quality. However, the over-application of chemical fertilizers in cherry cultivation leads to environmental issues such as ...
Sandra Pereira, Vânia Silva, Francisco Guedes, Fernando Raimundo, João Ricardo Sousa, Ana Paula Silva, Berta Gonçalves   +6 more
doaj   +1 more source

Water Marketing Program

, 1993
[Revised].; "January 1993.""The purpose of the water marketing program is to develop adequate water supply storage to meet, as nearly as practicable, present and anticipated municipal and industrial water needs through the purchase of water supply ...
Kansas Water Office.
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Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Low NaCl Concentrations Increase Cotyledon Growth in Chinese White Radish (Raphanus sativus L. var. longipinnatus Bailey) Seedlings via Aquaporin-Mediated Water Transport

Plants
This study aimed to elucidate the specific role of low NaCl concentrations, particularly 10 and 20 mM, in stimulating cotyledon growth in Chinese white radish (Raphanus sativus L. var. longipinnatus Bailey) seedlings.
Nutkamol Masepan, Sitthisak Intarasit, Aussara Panya, Jarunee Jungklang   +3 more
doaj   +1 more source