Results 71 to 80 of about 3,541,761 (309)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Root Architecture and Functional Traits of Spring Wheat Under Contrasting Water Regimes

Frontiers in Plant Science, 2020
Wheat roots are known to play an important role in the yield performance under water-limited (WL) conditions. Three consecutive year trials (2015, 2016, and 2017) were conducted in a glasshouse in 160 cm length tubes on a set of spring wheat (Triticum ...
Nidia Brunel-Saldias, Juan Pedro Ferrio, Juan Pedro Ferrio, Juan Pedro Ferrio, Abdelhalim Elazab, Massiel Orellana, Alejandro del Pozo   +6 more
doaj   +1 more source

Spectroscopic measurement of leaf water status [PDF]

1995 International Geoscience and Remote Sensing Symposium, IGARSS '95. Quantitative Remote Sensing for Science and Applications, 2002
A leaf drying experiment was carried out in the laboratory in which simultaneous spectral reflectance in the 350-2450 nm region, and leaf weights, were measured at 10 second intervals over a 40 minute period. As the leaf water weight dropped from approximately 60 to 38%, a nearly-linear rise in reflectance at all wavelengths beyond 1000 nm was observed.
A.F.H. Goetz, J.W. Boardman
openaire   +1 more source

Water saving through international trade of agricultural products [PDF]

, 2005
Many nations save domestic water resources by importing water-intensive products and exporting commodities that are less water intensive. National water saving through the import of a product can imply saving water at a global level if the flow is from ...
Chapagain, A.K., Hoekstra, A.Y., Savenije, H.H.G.   +2 more
core   +5 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Physiological Responses of Jatropha to Drought Stress in Coastal Sandy Land Conditions

Makara Seri Sains, 2012
Jatropha curcas L., an important tropical biofuel crop, is reputed for its drought resistance, however, its ability to perform in dry conditions has still hardly been investigated.
Bambang Djadmo Kertonegoro, Rukmini Kusmarwiyah, Prapto Yudono, I Gusti Made Arya Parwata, Didik Indradewa   +4 more
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Cover Crops Affect Performance of Organic Scarlotta Seedless Table Grapes Under Plastic Film Covering in Southern Italy

Agronomy, 2020
In sustainable or organic vineyard systems, the introduction of cover crops could represent a powerful tool for farmers to influence, positively, the agro-ecosystem by promoting the whole soil-plant system equilibrium.
Luigi Tarricone, Giambattista Debiase, Gianvito Masi, Giovanni Gentilesco, Francesco Montemurro   +4 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source