Results 61 to 70 of about 2,586,747 (309)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
npj Clean WaterThis study investigates the scale inhibition performance of a commercial polyacrylic acid-based (PAA) antiscalant used for drinking water production and its molecular weight fractions (≤ 500 Da, ≥ 500 Da).
S. A. Kaushik +5 more
doaj +1 more source
Water Supply Planning under Interdependence of Actions: Theory and Application [PDF]
, 1999 An ongoing water supply planning problem in the Regional Municipality of Waterloo, Ontario, Canada, is studied to select the best water supply combination, within a multiple-objective framework, when actions are interdependent.
Hipel, Keith W. +2 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Smart water supply system: a quasi intelligent diagnostic method for a distribution network
Applied Water Science, 2022 Constantly developing monitoring systems provide a large amount of raw data. In many cases, the operators of water supply systems (WSS) have already reached their perception limit for analysing information.
Dariusz Kowalski +2 more
doaj +1 more source
Optimizing operations of large-scale water supply networks: a case study [PDF]
, 2012 In this paper we propose a mathematical programming model for a large drinking water supply network and discuss some possible extensions. The proposed optimization model is of a real water distribution network, the largest water supply network in ...
Aghezzaf, El-Houssaine +2 more
core +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Accounting for Georgia's Public Water Supply [PDF]
, 2005 not available.
Phyllis Isley, Ulrich Ebensperger
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Organizational Water Footprint to Support Decision Making: a Case Study for a German Technological Solutions Provider for the Plumbing Industry [PDF]
, 2020 With water scarcity representing an increasing threat to humans, the environment and the economy, companies are interested in exploring how their operations and supply chains affect water resources globally.
Berger, Markus +6 more
core +1 more source