Results 81 to 90 of about 683,923 (312)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

From storage to retention: expanding California's options for meeting its water needs [PDF]

open access: yes, 2012
The California Roundtable on Water and Food Supply (CRWFS) is a consensus-based forum for thought leaders to uncover obstacles, identify solutions, and take action to enhance water security for agriculture, the public and the environment.
California Roundtable on Water and Food Supply, author
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Valuable elements in sludge from eight municipal wastewater treatment plants in relation to their recovery potential

open access: yesEnvironmental Sciences Europe
Background The management of sludge from municipal wastewater treatment plants (WWTPs) is a global issue, but also an opportunity for circular reuse. Recent data show that sludge reuse in agriculture has the highest share of all utilization routes in the
Dobril Valchev   +8 more
doaj   +1 more source

Report of the State Water-Supply Commission to the Legislature of New Jersey ...

open access: yes, 1908
Authorized by Chap. 25, Laws 1907; appendix included.Mode of access: Internet.Continued in: New Jersey Department of Conservation and Development annual report (1915).Supplement: Supplemental report of the State Water-Supply ...
New Jersey. Water-Supply Commission.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Source-Water Assessments and the Kentucky Long-Range County Water Supply Planning Program

open access: yes, 1999
Proceedings of the 1999 Georgia Water Resources Conference, March 30 and 31, Athens, Georgia.At present, water agencies are focusing on Source Water Assessments across the country due to the requirements of the 1996 Safe Drinking Water Act amendments. In
Morgan, David
core  

OTHER TITLES: Annual Compliance Report. Public Water Supply: Annual Compliance Report for 2018. Kansas Drinking Water Annual Compliance Report

open access: yes, 2020
This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas Department of Health and Environment, Bureau of Water, Public Water Supply Section
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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