Results 101 to 110 of about 686,576 (312)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Evaluation of a net launcher for capturing urban gulls

open access: yesWildlife Society Bulletin, 2014
The capture of birds is a common part of many avian studies but often requires large investments of time and resources. We developed a novel technique for capturing gulls during the non‐breeding season using a net launcher that was effective and ...
Daniel E. Clark   +4 more
doaj   +1 more source

Determinants of the influence of community participation on the sustainability of local system community-based sanitation programs in Temanggung Regency [PDF]

open access: yesE3S Web of Conferences
Community-based Sanitation (SANIMAS) is an activity to address sanitation problems in Indonesia. 88% of communities in Temanggung Regency dispose of domestic wastewater directly into the river without any prior treatment.
Sunaryo Laillia Rakhmawati   +1 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Other title: Public water supply survival guide [PDF]

open access: yes, 2009
application/pdfPublic Water Supply Survival Guide for the Consumer Confidence Report Rule Public Water Supply Survival Guide for the Filter Backwash Recycling Rule Public Water Supply Survival Guide for the Interim Enhanced Surface Water Treatment Rule ...
Kansas. Bureau of Water.
core  

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Kansas Public Water Supply Capacity Development Program: Report to the Governor, 2017 [PDF]

open access: yes, 2017
Water system capacity is the ability to plan for, achieve, and maintain compliance with applicable drinking water standards. Capacity consists of three elements: Technical, Financial, and Managerial (TFM). Technical Capacity or capability is the physical
Kansas. Bureau of Water. Public Water Supply Section
core  

Challenges in Tea Plantation-Based Small Community Water Safety Plan Implementation – A Sri Lankan Experience

open access: yesJournal of Tropical Forestry and Environment
This paper presents the challenges and scientific approach adopted to overcome those challenges for Rural WSP (RWSP) implementation for the water supply schemes (WSS) in the Sri Lankan Tea Plantation sector.
DT Udagedara   +8 more
doaj  

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