Results 101 to 110 of about 683,923 (312)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Kansas Public Water Supply Capacity Development Program Status Report, 2004-2010

, 2003
Kansas Public Water Supply Program Status Report for Fiscal Year 2004 Kansas Public Water Supply Program Status Report for Fiscal Year 2005 Kansas Public Water Supply Program Status Report for Fiscal Year 2006 Kansas Public Water Supply Program Status ...
Kansas. Bureau of Water. Public Water Supply Section.
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Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Challenges in Tea Plantation-Based Small Community Water Safety Plan Implementation – A Sri Lankan Experience

Journal of Tropical Forestry and Environment
This paper presents the challenges and scientific approach adopted to overcome those challenges for Rural WSP (RWSP) implementation for the water supply schemes (WSS) in the Sri Lankan Tea Plantation sector.
DT Udagedara, A.A.G.D. Amarasooriya, D.C. Herath, S.M. Rajapaksha, A. Kulathunge, P. Rajapaksha, G. Subasinghe, S.K. Weragoda, S.S. Garusinghe   +8 more
doaj  

THE WATER-SUPPLY OF CITIES. [PDF]

JAMA: The Journal of the American Medical Association, 1898
ABSTRACT This is one of the burning questions of the hour. It is not because there is a lack of water. We have an abundance of streams, from the smallest brook that rushes down the mountain side, meanders through the fields and meadows, between flowery banks, over gravelly beds or through rich soil in cultivated bottom lands to the great Father of ...
openaire   +1 more source

Root developmental responses to heterogeneous water and nitrogen supply [PDF]

, 2012
Better understanding of the interaction between the soil physical properties determining water and nitrate availability and the root proliferation and gene expression components of nutrient acquisition could contribute to food security, but may have been
Chapman, N., CHAPMAN, NICHOLAS
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Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Surveillance of Norovirus in Nationwide Groundwater Sources in South Korea: A Comprehensive Five-Year Study

Viruses
Groundwater is an essential drinking water source for humans. However, improper groundwater management leads to fecal contamination and waterborne diseases caused by viral pathogens.
Jung Eun Lee, Jihye Kim, Jihyun Kang, Kyung Seon Bae, Eung-Roh Park, Jeong-Ki Yoon   +5 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

OTHER TITLES: Annual Compliance Report. Public Water Supply: Annual Compliance Report for 2018. Kansas Drinking Water Annual Compliance Report

, 2019
This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas Department of Health and Environment, Bureau of Water, Public Water Supply Section
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