Results 101 to 110 of about 1,114,899 (313)
Water Resources ResearchBlue‐green roofs (BGRs), compared to traditional green roofs, can provide enhanced water storage capacity for stormwater management and drought mitigation.
Jiachang Wang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Determining Sustainable Development Density using the Urban Carrying Capacity Assessment System [PDF]
, 2004 Diverse urban problems in the capital region of Korea occur due to over-development and over-concentration which exceed the region’s carrying capacity.
Jeong, Yeunwoo +3 more
core
Residual capability of alkali binding by hydrated pozzolanic cements in long-service concrete structures [PDF]
, 2018 An experimental procedure was developed and applied to cement pastes made with two different pozzolanic cements (CEM IV/B (P) and CEM IV/B (V)) in order to ascertain the existence of a residual capability of alkali binding by long-term hydrated ...
Antonio Evangelista Paolini, And +2 more
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Sensitivity analysis of heat losses in distribution systems : impact of different buildings typologies [PDF]
, 2016 This paper focuses on the sensitivity of heat losses in collective heat distribution systems using a simplified calculation method. The methodology considers several parameters influencing the performance of heat distribution systems.
Janssens, Arnold +1 more
core
Time-dependent, species-specific effects of N:P stoichiometry on grassland plant growth [PDF]
, 2010 N and P have different eutrophication effects on grassland communities, yet the underlying mechanisms are poorly understood. To examine plant growth in response to the varying (relative) supply of N and P, we conducted a two-year greenhouse experiment ...
Fujita, Y. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
LandNeglecting ecosystem services has impeded sustainable urban–rural development, particularly in terms of the efficient flow of water supply services between urban and rural areas.
Fei Duan +6 more
doaj +1 more source