Results 51 to 60 of about 15,025,522 (243)

Impacts of Extreme Storms in Surface Water Resources, Systems, and Infrastructure—Evidence from Storm Daniel (2023) in Greece

GeoHazards
As the frequency and severity of extreme weather events may increase due to climate change, understanding their impacts on water systems, resources, and infrastructure becomes very important. This study contributes to the growing body of knowledge on how
Michalis Diakakis, Petros Andriopoulos, Andromachi Sarantopoulou, Ioannis Kapris, Christos Filis, Aliki Konsolaki, Emmanuel Vassilakis, Panagiotis Nastos   +7 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Urban scaling of water and electricity demand across the United States

Environmental Research: Infrastructure and Sustainability
As urban populations continue to grow, ensuring an adequate supply of water and electricity will be imperative. However, these resources are generally extracted in rural areas, creating tension during periods of limited availability.
Joy Adul, Vijay Bhaskar Chiluveru, Renee Obringer   +2 more
doaj   +1 more source

Benchmark Datasets for Fluid Flow Analysis

CSEE Journal of Power and Energy Systems
Fluid flow analysis, such as gas flow analysis, water flow analysis, etc., is a fundamental problem in integrated energy systems (IES). Datasets are significant for researchers to test their proposed models and algorithms for fluid flow analysis. In this
Wenhao Jia, Tao Ding, Ouzhu Han, Chenggang Mu, Hongji Zhang   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Water in the 2003 Virginia General Assembly

, 2003
The 2003 Virginia General Assembly convened on January 8 and adjourned on February 22, with a reconvened (“veto”) session on April 2. The legislature considered 3277 measures; 1585 passed and 1692 failed. The legislature also considered amendments to the
Virginia Water Resources Research Center
core  

Evaluating How Climate Adaptation Measures Affect the Interconnected Water‐Energy Resource Systems of the Western United States

Earth's Future
The Western US faces increasing water stress from the impacts of climate change, making it difficult to meet water demands for the region's cities, agriculture, and hydropower generators. Existing literature suggests that climate adaptation measures such
A. Singhal, J. K. Szinai, D. Yates, A. D. Jones   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source