Results 81 to 90 of about 2,565,844 (218)

Stories of a water-table: anomalous depressions, aquitard breaches and seasonal implications, Shelby County, Tennessee, USA. [PDF]

Environ Monit Assess, 2023
Lozano-Medina D, Waldron B, Schoefernacker S, Antipova A, Villalpando-Vizcaino R.   +4 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Plate Load Tests on an Unsaturated Sand-Kaolin Mixture with Varying Water Table. [PDF]

Sensors (Basel), 2022
Tang Y, Chen C, Qian B, Ren J, Guan Y.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Genetic and Iterative Metaheuristics‐Informed Algorithms for Precision Shallow Groundwater Modeling and Drought Inference

Journal of Geophysical Research: Machine Learning and Computation
Cokriging is a widely used geostatistical method for modeling the shallow groundwater table, often incorporating digital elevation models (DEMs) as secondary variables.
Massimiliano Schiavo, Daniele Pedretti
doaj   +1 more source

Lowering water table reduces carbon sink strength and carbon stocks in northern peatlands. [PDF]

Glob Chang Biol, 2022
Kwon MJ, Ballantyne A, Ciais P, Qiu C, Salmon E, Raoult N, Guenet B, Göckede M, Euskirchen ES, Nykänen H, Schuur EAG, Turetsky MR, Dieleman CM, Kane ES, Zona D.   +14 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Typha for paludiculture-Suitable water table and nutrient conditions for potential biomass utilization explored in mesocosm gradient experiments. [PDF]

Ecol Evol, 2022
Haldan K, Köhn N, Hornig A, Wichmann S, Kreyling J.   +4 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Response of soil respiration to changes in soil temperature and water table level in drained and restored peatlands of the southeastern United States. [PDF]

Carbon Balance Manag, 2022
Swails EE, Ardón M, Krauss KW, Peralta AL, Emanuel RE, Helton AM, Morse JL, Gutenberg L, Cormier N, Shoch D, Settlemyer S, Soderholm E, Boutin BP, Peoples C, Ward S.   +14 more
europepmc   +1 more source