Results 31 to 40 of about 2,142,099 (244)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Water exercise and health promotion
During water exercise, it was established that heart rate, oxygen uptake and body temperature respond to the influence of water pressure, temperature, buoyancy, and viscosity.
Sho Onodera +7 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Deep coaxial borehole heat exchangers (DCBHEs) exhibit superior thermal performance compared to conventional shallow systems, particularly in cold regions.
Yibin Huang +4 more
doaj +1 more source
Bacterial kidney disease (BKD) is widespread in many areas of the world and can cause substantial economic losses for the salmon aquaculture industry.
Marco Rozas-Serri +17 more
doaj +1 more source
Water temperature is a key dimension of estuaries that can influence important biological processes including organismal growth, survival, and habitat use.
Phoebe L. Gross +7 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
LOW IRRIGATION WATER TEMPERATURES have already begun to reach problem proportions in the production of certain crops in northern California and may become far more common, especially in the northern parts of the State, as our water storage program ...
F Raney
doaj
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Climatic Determinants of Changes in the Ice Regime of Carpathian Rivers
The study addresses the influence of climatic conditions on changes in the ice regime of Carpathian rivers (Central Europe) over the period 1980–2020.
Fukś Maksymilian, Wiejaczka Łukasz
doaj +1 more source

