Results 41 to 50 of about 2,557,612 (293)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Remote Sensing, 2017 Although changes in water temperature influence the rates of many ecosystem processes in lakes, knowledge of the water temperature regime for large floodplain lake systems subjected to multiple stressors has received little attention.
Yunliang Li +4 more
doaj +1 more source
Features of under-ice zooplankton in Lake Pleshcheyevo (Yaroslavl Region, Russia)
Трансформация экосистем, 2023 In March 2019, we studied the taxonomic composition, vertical and horizontal distribution of under-ice zooplankton in Lake Pleshcheyevo and revealed that its quantity (abundance 11.5–13.8 thous.ind./m3, biomass
Svetlana M. Zhdanova, Mikhail I. Malin
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Evaluating Stress-Mediated Microbial Pathogenesis in Golden Shiners, Notemigonus crysoleucas
Frontiers in Physiology, 2022 Flavobacterium covae (columnaris) is a microbial pathogen of the Golden Shiner (Notemigonus crysoleucas), a principal bait species. We investigated the effects of density and water temperature on the survival of fish subjected to a columnaris challenge ...
Sindhu Kaimal +5 more
doaj +1 more source
Water desalination using a temperature gradient
, 2019 A new concept for reverse osmosis is identified based on the use of a temperature gradient instead of pressure. When the temperature of the permeate-side of the membrane is higher than the feed-side then a significant driving force exists for water ...
Tokay, Begum +4 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Water exercise and health promotion
Journal of Physical Fitness and Sports Medicine, 2013 During water exercise, it was established that heart rate, oxygen uptake and body temperature respond to the influence of water pressure, temperature, buoyancy, and viscosity.
Sho Onodera +7 more
doaj +1 more source
, 2008 Water temperature is an important determinant in many aquatic biological processes, including the growth and development of malaria mosquito (Anopheles arabiensis and A. gambiae) immatures.
Paaijmans, K.P. +3 more
core +1 more source