Results 61 to 70 of about 5,055,926 (284)

Climatic Determinants of Changes in the Ice Regime of Carpathian Rivers

open access: yesQuaestiones Geographicae
The study addresses the influence of climatic conditions on changes in the ice regime of Carpathian rivers (Central Europe) over the period 1980–2020.
Fukś Maksymilian, Wiejaczka Łukasz
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Efficient and low-cost temperature automated system for aquariums in fry hatcheries using control algorithms

open access: yesRevista de Ciencias Sociales, 2023
The purpose of this research is aimed to bring an alternative solution for the raising of fry in aquatic ponds, through the control and monitoring of water temperature, in order to optimize their development and growth, regardless of the habitat where ...
Julio Macedo   +3 more
doaj  

Variational method in the design of an optimum solar water heater storage tank [PDF]

open access: yes, 2007
Solar water heaters are now have been accepted as a reliable source of providing hot water heating in many domestic homes and are becoming more popular. Unfortunately, solar water heaters are still considered luxurious hardware in Malaysia. A cheaper and
Darus, Amer Nordin, Misha, Suhaimi
core  

Water temperature modeling in the Garonne River (France) [PDF]

open access: yes, 2010
Stream water temperature is one of the most important parameters for water quality and ecosystem studies. Temperature can influence many chemical and biological processes and therefore impacts on the living conditions and distribution of aquatic ...
Croze, Olivier   +3 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

THE IMPORTANCE OF AQUATIC THERAPY IN THE TREATMENT OF THE CEREBRAL PALSY IN PRESCHOOL AGE CHILDREN [PDF]

open access: yesAnnals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2019
Cerebral palsy (CP) it is known as a condition that occurs in infants or in fetal development of encephalon. The main purpose in this study was to highlight the importance of aquatic therapy used as an alternative method or in parallel with ...
Haidamac Ana
doaj  

Spatial and temporal changes in assemblage structure of zooplankton and pelagic fish in the eastern Bering Sea across varying climate conditions

open access: yesИзвестия ТИНРО, 2015
Zooplankton and pelagic fish samples collected on the eastern Bering Sea shelf in late summer 2003-2010 were used to evaluate spatial and temporal changes in the plankton and nekton community structure.
Lisa B. Eisner   +2 more
doaj   +1 more source

Optimizing production efficiencies of hot water units using building energy simulations : trade-off between Legionella pneumophila contamination risk and energy efficiency [PDF]

open access: yes, 2019
The energy needed for domestic hot water represents an important share in the total energy use of well-insulated and airtight buildings. One of the main reasons for this high energy demand is that hot water is produced at temperatures above 60°C to ...
De Backer, Lien   +2 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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