Results 61 to 70 of about 11,786,465 (330)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Inversion of Initial Field Based on a Temperature Transport Adjoint

Journal of Marine Science and Engineering, 2021
The setting of initial values is one of the key problems in ocean numerical prediction, with the accuracy of sea water temperature (SWT) simulation and prediction greatly affected by the initial field quality.
Shengyi Jiao, Shengmao Huang, Jianfeng Wang, Xianqing Lv   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Water-level data from observation wells in the northern panhandle of Texas [PDF]

, 1971
By A.
Wyatt, A. Wayne
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Water-level data from observation wells in the southern High Plains of Texas, 1965-70 [PDF]

, 1970
By A.
Wyatt, A. Wayne
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Monitoring Thermal Exchange of Hot Water Mass via Underwater Acoustic Tomography with Inversion and Optimization Method

Remote Sensing
Thermal exchange of underwater water mass caused by marine heat wave is a hot point of research recently. In particular, because the water temperature observation along hot water mass transportation is hard work. Acoustic tomography is an advanced method
Shijie Xu, Fengyuan Yu, Xiaofei Zhang, Yiwen Diao, Guangming Li, Haocai Huang   +5 more
doaj   +1 more source

Report on oceanographic observation by the 20th Japanese Antarctic Research Expedition 1978-1979

Antarctic Record, 1982
On board the icebreaker FUJI from November 1978 to April 1979,the physical and chemical oceanographic observations were carried out, as part of the routine programs of the 20th Japanese Antarctic Research Expedition.
Motoyuki Suzuki, Takao Kurano
doaj   +1 more source

Influence of hydroelectric development on water temperature downstream the Pubugou hydropower station of the Dadu River

Shui kexue jinzhan, 2016
To research the influence of hydroelectric development on water temperature of the Dadu River,a comparative analysis was done to describe the characteristics of temporal and spatial water temperature changes downstream river reach after and before ...
TUO Youcai, ZHOU Chenyang, LIANG Ruifeng, LI Kefeng   +3 more
doaj   +1 more source