Results 81 to 90 of about 14,286,481 (305)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Water in the 2005 Virginia General Assembly
, 2005 The 2005 Virginia General Assembly convened January 12 and adjourned February 27, with a reconvened (“veto”) session on April 6. The legislature considered 3363 measures (2938 introduced this year and 425 carried over from last year); 1610 measures ...
Virginia Water Resources Research Center
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, 2014 This newsletter features articles on water-related science, policy, and law. Distributed to state agency representatives, faculty, students and interested citizens, it aims to provide current information, statistics, news, and notices related to water ...
Virginia Water Resources Research Center
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Desalination and Water TreatmentModern agriculture faces critical challenges from climate change, water scarcity, and soil degradation that threaten global food security for the projected 9.7 billion people by 2050. This review examines multifunctional hydrogel systems as an innovative
Gamareldawla H.D. Agbna +2 more
doaj +1 more source
Journal of Chemistry, 2019 Coagulation and sedimentation performances of aluminum sulphate and ferric chloride were comparatively investigated in presence of Grewia spp. biopolymer for the treatment of concentrated laterite suspensions.
Kameni Ngounou M. Bernard +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Water in the 2010 Virginia General Assembly
, 2010 The 2010 Virginia General Assembly convened January 13 and adjourned March 13. The reconvened (“veto”) session was held April 21. During the session, the Assembly considered 2964 measures, passing 1598 of them, defeating 1093, and continuing 273 until ...
Virginia Water Resources Research Center
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Assessment of concentration physicochemical parameters and heavy metals in Kızılırmak River, Turkey [PDF]
, 2017 Kızılırmak is the longest river of Turkey and the most important one as a resource for various water uses. Therefore Kızılırmak river basin is under pressure from a diverse range of human activities. Six stations were sampled along the Kızılırmak river
Aras, Seval +3 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source