Results 81 to 90 of about 21,485,299 (311)

A Novel Vane-type Oil-water Separator

open access: yesShiyou jixie, 2020
In the late stage of oil well production, the water cut is getting higher and higher, which puts forward higher requirements for downhole oil-water separators. A new type of vane type oil-water separator is introduced.
Zhan Min   +6 more
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Water in the Alluaudite Type-Compounds

open access: yesMinerals, 2021
In this study, a new cobalt arsenate belonging to the alluaudite supergroup compounds with the general formula of Co-3(AsO4)(0.5+x)(HAsO4)(2-x)(H2AsO4)(0.5+x)[(H,)(0.5)(H2O,H3O)(0.5)](2)(x+) (denoted as CoAsAllu) was synthesized under hydrothermal conditions.
Đorđević, Tamara   +3 more
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

A novel water optical types framework for Chinese inland waters with the application of multitype satellite sensor

open access: yesInternational Journal of Digital Earth
Optical Water Type (OWT) analysis is crucial for comprehending water composition and quality, key factors in assessing water quality over extensive areas. However, China’s inland waters lack a standardized system for such analysis.
Ruidan Sang   +4 more
doaj   +1 more source

Water producing mechanisms of carbonate reservoirs gas wells: A case study of the Right Bank Field of Amu Darya, Turkmenistan

open access: yesPetroleum Exploration and Development, 2017
The mechanisms of carbonate gas reservoirs were systematically studied with the Right Bank Field of Amu Darya Gas Field, Turkmenistan, as an example. Water produced from the reservoirs has three sources, condensate water, engineering fluids and formation
Youyou CHENG   +11 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Evaluating the Energy and Thermal Performance of a Water-Cooled Condenser Using Reverse Osmosis Effluent in Residential Purifiers

open access: yesApplied Sciences
Reverse osmosis (RO) water purifiers produce a large volume of reject water, which is typically discarded, leading to water wastage and resource inefficiency.
Jae Won Lee
doaj   +1 more source

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