Results 51 to 60 of about 3,375,307 (312)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

EVALUATION OF CHEMICAL REMEDIATION TECHNIQUES OF P8-CONTAMINATED SOILS USING KINETIC APPROACH [PDF]

open access: yesJournal of Soil Sciences and Agricultural Engineering, 2005
This study investigated the effect of rock phosphate (RP). polyvinyl acetate butyl acrylate emulsion 50% active material w/w (PVAc) and Humic acid (HA) as natural and synthetic materials applied in remediation.
M.A. Abou Seeda, A. M. Zaghloul
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Water Use [PDF]

open access: yesAnnual Review of Environment and Resources, 2003
Water managers and planners are slowly beginning to change their perspective and perceptions about how best to meet human needs for water; they are shifting from a focus on building supply infrastructure to improving their understanding of how water is used and how those uses can best be met.
openaire   +2 more sources

Pattern of Water Use at the United Arab Emirates University

open access: yes, 2019
In this study, indoor water use at the United Arab Emirates University (UAEU) was assessed for three years (2016, 2017, and 2018). A geographic information system (GIS) was employed to determine where water use is high within the university, when and why
M. M. Yagoub   +4 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

What does rebounding water use look like? An examination of post-drought and post-flood water end-use demand in Queensland, Australia

open access: yes, 2013
Rebounding water use behaviour has been observed in communities that have experienced plentiful water supply following a very dry period. However, the drivers of such rebounds in water consumption are varied and not well understood.
Beal, Cara   +2 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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