Results 61 to 70 of about 2,659,137 (363)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Engineered biochar improves nitrogen use efficiency via stabilizing soil water-stable macroaggregates and enhancing nitrogen transformation [PDF]

, 2023
Zaid Khan, Xu-Jian Yang, Youqiang Fu, Stephen Joseph, Mohammad Nauman Khan, Muhammad Ayoub Khan, Intikhab Alam, Hong Shen   +7 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Water use efficiency of Irish dairy processing [PDF]

Journal of Dairy Science, 2019
Dairy processing uses a significant amount of water for processing and cleaning. Withdrawing and distributing water and treating wastewater represent significant costs to the Irish dairy processing industry. Stringent discharge limits also add pressure for water use efficiency, particularly during peak production months.
M.-J. Yan, N.M. Holden
openaire   +2 more sources

Dramatic increase in water use efficiency with cumulative forest disturbance at the large forested watershed scale [PDF]

, 2021
Krysta Giles‐Hansen, Xiaohua Wei, Yiping Hou   +2 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Water use of wheat, corn and sunflower in the semiarid pampas [PDF]

Ciencia del Suelo, 2017
Crop water use in semiarid environments allows designing management strategies to improve water use efficiency. Our objective was to estimate wheat (Triticum aestivum L.), maize (Zea mays L.) and sunflower (Helianthus annuus L.) water use in the Semiarid
Alfredo A Bono, Roberto Álvarez, Josefina L de Paepe   +2 more
doaj  

Technical efficiency of water use and its determinants, study at smallscale irrigation schemes in North-West Province, South Africa [PDF]

, 2007
This paper analyses the efficiency with which water is used in small-scale irrigation schemes in North-West Province in South Africa and studies its determinants.
Buysse, Jeroen, D'Haese, Luc, D'Haese, Marijke, Speelman, Stijn   +3 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Biofuel, land and water: maize, switchgrass or Miscanthus?

Environmental Research Letters, 2013
The productive cellulosic crops switchgrass and Miscanthus are considered as viable biofuel sources. To meet the 2022 national biofuel target mandate, actions must be taken, e.g., maize cultivation must be intensified and expanded, and other biofuel ...
Qianlai Zhuang, Zhangcai Qin, Min Chen
doaj   +1 more source