Results 81 to 90 of about 25,292,297 (311)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Managing Externalities: Opportunities to improve urban water use [PDF]
This report identifies a range of opportunities to adopt policies that improve the efficiency of water use, reduce the extent of undesired externalities and to enhance the quality of urban environments.Australia;urban water;externalities ...
Mike Young
core
, 2018 In an irrigated multi-crop production system, farmers make decisions on the land allocated to each crop, and the subsequent irrigation water application, which determines the crop yield and irrigation water use efficiency. This study analyzes the effects
Raymond Massey +3 more
core +1 more source
, 2020 Rice is one of the most important food crops in China and is also the largest user of agricultural water. Experiments were conducted for two consecutive years at two locations of Jiangsu province to study the effect of four irrigation methods with four ...
Liang Sen +4 more
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
International Journal of Bio-Resource and Stress Management, 2016 A field experiment was conducted to study adaptation of potato to climate aberrations at Central Potato Research Station, Gwalior, India which is located in Central Plains of India.
S. P. Singh
doaj
Efficiency and equity considerations in pricing and allocating irrigation water [PDF]
Economic efficiency has to do with how much wealth a given resource base can generate. Equity has to do with how that wealth is to be distributed in society. Economic efficiency gets far more attention, in part because equity considerations involve value
Tsur, Yacov, Dinar, Ariel
core
Water Use Efficiency in Young Citrus Trees on Metalized UV Reflective Mulch Compared to Bare Ground
, 2023 A precise estimation of plant water use is crucial for efficient irrigation management and understanding of plant–water interactions. Metalized-polyethylene mulch as a ground cover, combined with irrigation management, can improve water and ...
Hossein Ghoveisi +3 more
core +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source